Primobolan is a Dihydrostestosterone (DHT) derivative (a modified form of DHT), where it contains a double-bond between carbon atoms 1 and 2 in the DHT structure. This allows stabilization of the 3-keto group which increases the anabolic effect. A 1-methyl group is also added to the structure, which allows it to resist hepatic (liver) metabolism and breakdown.
The injectable format (Methenolone Enanthate) in particular is Methenolone along with the Enanthate ester bound tovit. Specifically, Enanthate’ is Enanthoic acid (also known as carboxylic acid), but once bound to Methenolone it is known as an ester bond. Enanthoic acid is chemically bonded to the 17-beta hydroxyl group on the Methenolone structure. The addition of this ester augments the hormone’s release rate and half-life to favor a longer release profile. The primary reason for the augmentation of its half-life and release rate is because once Methenolone Enanthate enters the bloodstream, enzymes work to break the bond between the ester and the hormone, over a certain amount of time. The half-life of Primobolan is 10 - 14 days.
Primobolan being a DHT-derivative, it cannot be aromatized by the aromatase enzyme into Estrogen at any dose. Due to this it completely voids the potential for any of the following estrogen-related side effects: water retention, elevated blood pressure (as a result of water retention), possible fat gain/retention, and gynecomastia. Primobolan is regarded by most athletes as preferred for pre-contest and cutting cycles. Primobolan is commonly known as being a ‘mild’ anabolic steroid, it still exhibits suppression of endogenous Testosterone production and HPTA function. It is still recommended to follow a proper PCT (Post Cycle Therapy) after discontinuation.
Many bodybuilders often stack Primobolan with Testosterone Propionate (or Testosterone Enanthate) and use it for the first 8 weeks of a cycle in order to assist in the retention of muscle mass during periods of low caloric intake. Beginner dosages normally start at about 400mg per week. Intermediate dosages range between 400 – 700mg per week, and advanced users may go as high as 800 – 1,000mg per week. Female dosages are usually in the range of 50 – 100mg per week (controlling possible virilization at higher dosages).
Acne:Yes, In High Doses
Water retention: Low
High blood pressure: Rare
DHT Conversion: No
Decreased HPTA function: Yes
Active life: 10-14 days
Drug class: Anabolic/Androgenic steroid (for injection)
Average dose: Men 400 - 1000 mg/week